Projects

Some ongoing or past research projects coordinated or supported by BSE RDAC.

BERD Core - OSCTR

• In response to the IDeA Program Infrastructure for Clinical and Translational Research RFA, the University of Oklahoma Health Sciences Center will serve as the primary academic health center and will partner with the Oklahoma Medical Research Foundation, Oklahoma City Area Inter-Tribal Health Board, Oklahoma Physician Resource/Research Network, OU-Norman and OU-Tulsa to form the Oklahoma Shared Clinical and Translational Resources (OSCTR). Furthermore, we have forged affiliated partnerships for select projects with institutions from other IDeA-eligible states, including University of Arkansas for Medical Sciences, Alaskan Native Tribal Health Consortium and the Medical University of South Carolina. The OSCTR will provide clinical and translational research infrastructure to a wide variety of investigators who are committed to understanding disease processes and improving the health outcomes of people in IDeA states which have some of the poorest health ratings in the country. This 5-year NIH-funded grant award totals $20.3 million dollars.
• The aims of the Biostatistics, Epidemiology, and Research Design (BERD) Key Component Activities (KCA) are to enhance the quality and productivity of research conducted by OSCTR investigators by providing consultative and collaborative support in the disciplines of biostatistics, epidemiology, and informatics; to provide education, training and career development for clinical and translational researchers in the disciplines of biostatistics and epidemiology; and to advance the disciplines of biostatistics and epidemiology through the development and application of novel research designs and analytic methods.

American College of Phlebology

• “Development of a U.S. Consensus Document on the Performance of Endovenous Foam Sclerotherapy”
• Suman Rathbun, MD (Principal Investigator) OUHSC Cardiovascular Disease Section
• The purpose of this project is to conduct a systematic review of the published literature with the goal of providing quality improvement guidelines regarding safety and efficacy for the performance of foam sclerotherapy where evidence exists and to conduct a comprehensive questionnaire of those performing foam sclerotherapy in the U.S. to describe practice patterns and identify areas of common usage and methodology.

Southern Plains Inter-Tribal Epidemiology Center: American Indian Health Disparities Program Evaluation

• Janis Campbell, PhD (Principal Investigator), OUHSC Department of Biostatistics and Epidemiology
• The purpose of the project is to evaluate the process, objectives and long-term goals, and project impact of the Southern Plains Inter-Tribal Epidemiology Center: American Indian Health Disparities Program.

Robert Wood Johnson Foundation

• Management of Obstructive Sleep Apnea by Primary Care Providers
• James Mold, MD (Principal Investigator), OUHSC Department of Family and Preventive Medicine .
• The purpose of this project is to conduct a survey regarding the management of obstructive sleep apnea by primary care providers in Oklahoma.

NIH/NIDDK

• Lipoproteins and PEDF in the Vascular Complications of Diabetes
• Timothy Lyons, MD, FRCP (Principal Investigator), OUHSC Section of Diabetes and Endocrinology
• The major goals of this project are to determine and compare the relationships between NMR-defined lipoprotein subclasses and PEDF levels with cardiovascular disease, retinopathy and nephropathy complications in Type 1 and Type 2 diabetes.

Oklahoma State Department of Health

• “Dental Health Needs Assessment”
  • The purpose of this needs assessment is to determine the proportion of Oklahoma children who have received protective sealants on one or more permanent molars.
• “Biostatistical Support for Tobacco Use Prevention Service Projects”
  • The mission of the Tobacco Use Prevention Service is to improve the health of Oklahomans of all ages and populations through community partnerships that prevent tobacco use among youth, reduce tobacco dependence, and promote smoke-free environments.

Oklahoma Tobacco Research Center

• “Biostatistical Support for Tobacco Research Center Projects”
• The purpose of the Tobacco Research Center is to identify, evaluate and disseminate best practices for tobacco prevention, intervention and control in order to reduce tobacco use and tobacco-related cancer incidence and mortality in the State of Oklahoma.

• Oklahoma Insurance Department
  • “Engaging the Public in Designing a Basic Benefits Package”
  • The objective of this project was to determine the scope of insurance coverage that can and should be offered under a low cost, basic health insurance policy for Oklahomans.

1. Patel, J.H., Stoner, J.A., Owora, A., Mathew, S.T., Thadani, U. (2009) “Evidence for using clopidogrel alone or in addition to aspirin in post coronary artery bypass surgery patients”. Am J Cardiol. 103(12):1687-93.
2. Maple, J.T., Keswani, R.N., Hovis, R.M., Saddedin, E.Z., Jonnalagadda, S., Azar, R.R., Hagen, C., Thompson, D.M., Waldbaum, L., Edmundowicz, S.A. (2009). Carbon dioxide (CO2) insufflation during endoscopic retrograde cholangiopancreatography (ERCP) for the reduction of post-procedure pain: a randomized, double-blind controlled trial. Gastrointestinal Endoscopy. 70(2):278-83.
3. Ozcan, M.S., Thompson, D.M., Cure, J., Hine, J.R., & Roberts, P.R. (2009). Same-patient reproducibility of state entropy: Comparison of simultaneous bilateral measurements during general anesthesia. Anesthesia & Analgesia, 108, 1830–1835.