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The College of Public Health provides quality graduate and professional education for both public health practice professionals and research scientists. The OU College of Public Health is one of only 38 accredited schools of public health in the United States. A multi-disciplinary faculty prepares students for public health practice in five core areas; biostatistics, epidemiology, health administration and policy, health promotion sciences and occupational and environmental health and in the area of public health preparedness and terrorism emergency response. In addition, doctoral programs prepare public health research scientists in each of the five core areas. The College conducts classes at the OU Health Sciences Center in Oklahoma City and OU Schusterman Center in Tulsa. A state-of-the-art distance education program delivers courses to remote sites throughout the state and region.

An active research program greatly enhances the academic environment of the college. Studies in issues as varied as air quality, teen pregnancy prevention, cardio-vascular disease prevention, obesity prevention, and tobacco use prevention are ongoing. The college also has major initiatives related to American Indian Health. The Southwest Center for Public Health Preparedness was established at the college in 2002 to improve the response capacity of the public health workforce to terrorism and other threats. The Center for Biosecurity Research conducts interdisciplinary research aimed at enhancing protection against biological weapons and emerging infectious diseases.

The OU College of Public Health has strong working partnerships with state, national and international health agencies. Students have rich opportunities for both fieldwork experiences and multidisciplinary projects.